Paracetamol-induced hepatotoxicity at recommended dosage. Agranulocytosis, plasmacytosis, and thrombocytosis followed by a leukemoid reaction due to acute acetaminophen toxicity. Gursoy M, Haznedaroglu IC, Celik I, Sayinalp N, Ozcebe OI, Dundar SV. Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: analysis of instances of therapeutic misadventure. Is Tylenol (acetaminophen) an anti-inflammatory drug?ġ.Can you take paracetamol (acetaminophen) with antibiotics?.Is acetaminophen (Tylenol) an NSAID Drug?.Is Tylenol (acetaminophen) a blood thinner?.How long does it take for Tylenol to start working?. Is it safe to take acetaminophen every day?.Advil (ibuprofen) & Tylenol (acetaminophen) together, is it safe?.Can you take tramadol with acetaminophen, ibuprofen, or aspirin?.How long does Percocet stay in your system?.Acetaminophen vs Ibuprofen: Which is better?.What is paracetamol / panadol called in the US?.What medications cause liver enzymes to be elevated?.What's the best sore throat medicine to use?.Rare (0.01% to 0.1%): Malaise Frequently asked questions Very rare (less than 0.01%): Pemphigoid reaction, pustular rash, Lyell syndrome RespiratoryĬommon (1% to 10%): Dyspnea, abnormal breath sounds, pulmonary edema, hypoxia, pleural effusion, stridor, wheezing, coughing CardiovascularĬommon (1% to 10%): Peripheral edema, hypertension, hypotension, tachycardia, chest pain MetabolicĬommon (1% to 10%): Hypokalemia, hyperglycemia Nervous systemįrequency not reported: Dystonia MusculoskeletalĬommon (1% to 10%): Muscle spasms, trismus PsychiatricĬommon (1% to 10%): Insomnia, anxiety GenitourinaryĬommon (1% to 10%): Infusion site pain, injection site reactions OcularĬommon (1% to 10%): Periorbital edema Other Rare (less than 0.1%): Serious skin reactions such as acute generalized exanthematous pustulosis, Stevens-Johnson syndrome, and toxic epidermal necrolysis Very rare (less than 0.01%): Thrombocytopenia, leucopenia, neutropenia Dermatologic Postmarketing reports: Anaphylaxis, hypersensitivity reactions HematologicĬommon (1% to 10%): Anemia, postoperative hemorrhage Very common (10% or more): Nausea (up to 34%), Vomiting (up to 15%)Ĭommon (1% to 10%): Abdominal pain, diarrhea, constipation, dyspepsia, enlarged abdomenįrequency not reported: Dry mouth Hypersensitivity Rare (less than 0.1%): Increased hepatic transaminasesįrequency not reported: Liver failure Gastrointestinal HepaticĬommon (1% to 10%): Increased aspartate aminotransferase Injection site pain and injection site reaction have been reported with the IV product. The most commonly reported adverse reactions have included nausea, vomiting, constipation. In general, acetaminophen (the active ingredient contained in Tylenol Extra Strength) is well-tolerated when administered in therapeutic doses. swelling, pain, or tenderness in the upper abdomen or stomach areaĪpplies to acetaminophen: compounding powder, intravenous solution, oral capsule, oral granule effervescent, oral liquid, oral powder, oral powder for reconstitution, oral suspension, oral tablet, oral tablet chewable, oral tablet disintegrating, oral tablet extended release, rectal suppository.Get emergency help immediately if any of the following symptoms of overdose occur while taking acetaminophen: Symptoms of overdose sores, ulcers, or white spots on the lips or in the mouth.sore throat (not present before treatment and not caused by the condition being treated).pain in the lower back and/or side (severe and/or sharp).
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